Photoredox

3 insights in this topic

Blue Light-Mediated Decarboxylative Coupling Transforms Carboxylic Acid Feedstocks
Synthesis

Blue Light-Mediated Decarboxylative Coupling Transforms Carboxylic Acid Feedstocks

A simple photocatalytic system enables direct decarboxylative coupling of abundant carboxylic acids with alkenes, providing atom-economical routes to functionalized molecules.

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Photoredox-Mediated Peptide Stapling Enables Selective Protein-Protein Interaction Inhibitors
Biology

Photoredox-Mediated Peptide Stapling Enables Selective Protein-Protein Interaction Inhibitors

A novel photoredox approach for installing hydrocarbon staples into peptides yields cell-permeable inhibitors with enhanced proteolytic stability and binding affinity.

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Dual Nickel-Photoredox Catalysis Enables Unprecedented C-H Functionalization
Photoredox

Dual Nickel-Photoredox Catalysis Enables Unprecedented C-H Functionalization

Researchers demonstrate a new dual catalytic system combining nickel and photoredox catalysis to achieve direct C-H bond functionalization under mild conditions, opening pathways for late-stage drug modification.

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